Reinke's crystals in perivascular and peritubular Leydig cells

Author(s)
Viviana Kozina, Ljerka Banek, Nikola Knezevic, David Geist, Lucie Kubinová, Marin Kosovic, Christian Rentenberger, Andreja Vukasovic, Davor Jezek
Abstract

The human testis is composed of seminiferous tubules and interstitium. Within the interstitium, residing Leydig cells can occasionally bear Reinke's crystals. The aim of the current study was to investigate Reinke's crystals in perivascular and peritubular Leydig cells in control and infertile (cryptorchid) testes. For that purpose, bright field, confocal and transmission electron microscopy were applied. The crystal lattice was investigated by Fast Fourier Transformation and the number of crystals determined by stereology. Results of the study indicated a higher number of crystals in perivascular cells (in the both control and cryptorchid group). Moreover, when control and cryptorchid specimens were compared for the presence of the crystal, a higher number of Reinke's crystals was recorded in cryptorchid testes. Thick sections of the crystal were extremely helpful in yielding crystallographic data which confirmed a trigonal crystal structure of the lattice. The exact molecular composition of crystal's microfilaments still remains unknown.

Organisation(s)
Physics of Nanostructured Materials
External organisation(s)
University of Zagreb, Czech Academy of Sciences
Journal
Croatica Chemica Acta
Volume
84
Pages
159-167
No. of pages
9
ISSN
0011-1643
DOI
https://doi.org/10.5562/cca1814
Publication date
2011
Peer reviewed
Yes
Austrian Fields of Science 2012
1030 Physics, Astronomy, 106006 Biophysics
Portal url
https://ucrisportal.univie.ac.at/en/publications/4699a3cf-2613-4df5-9b37-0b8cfd6d9663